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These are transformative numbers by the historical standards of pharmacological obesity treatment, where prior-generation agents rarely exceeded 5% placebo-adjusted efficacy

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Concerning prefrontal cortical TNF-, Doxorubicin and Cyclophosphamide treatment revealed a significant elevation in TNF- level as compared to the control group by 1.29 folds

Sensitivity analyses with alternative covariates confirmed the robustness of the findings