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Medical conditions treated by Semaglutide, such as obesity, diabetes, and related metabolic disorders, can alternatively be addressed with these other medications

Researchers also observed a trend of increased mtDNA 4977 mutations among TDT patients with age, while no significant change was observed in the control group

Trial support is deep: STEP (semaglutide, NEJM 2021), SURMOUNT (tirzepatide, NEJM 2022), and SURMOUNT-OSA (tirzepatide in obstructive sleep apnea, NEJM 2024)