LEADER Trial The renal outcome in this trial was a composite of new-onset persistent macroalbuminuria, persistent doubling of the serum creatinine level, end-stage renal disease, or death due to renal disease
In the postpartum period, the use of NSAIDs does not lead to an increase in blood pressure in women who have experienced hypertensive disorders during pregnancy ( Glucocorticoids Glucocorticoids may be cautiously used during pregnancy to manage lupus nephritis flares if clinically appropriate ( Azathioprine Azathioprine (AZA) is considered a suitable option during pregnancy when benefits outweigh potential risks
Most GLP-1 medications are proteins, and like any protein, they are sensitive to heat and light
Not all patients experience clinically meaningful improvements in cholesterol, and some may require additional lipid-lowering therapy regardless of weight loss
Slower dose increases (titration) reduce the intensity of early side effects
Mounjaro is generally more expensive than Retatrutide, with considerations on cost, accessibility, and availability guiding the choice between these two medications for weight management
