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In contrast, neural cells may rely on the Nrf2-SLC7A11 axis to maintain antioxidant capacity, so quercetin protects cells by activating this axis

Likewise, several other chemotherapeutic agents, such as platinum complexes (e.g., cisplatin) [194] and sorafenib [195], enhance mitochondrial ROS production or hinder the antioxidant system, thereby causing heightened ROS levels within cancer cells

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For selected symptomatic patients please review Figure 1: B 12 Test Result Review and Process Algorithm for Patients with Risk Factor for B 12 Deficiency* and/or Non-specific** or Specific Symptom of B 12 Deficiency

35 , e21286 (2021)

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