In the SURMOUNT-5 head-to-head trial against semaglutide, tirzepatide at maximum dose produced 20.2% weight loss compared to semaglutide at 13.7%
doi: 10.2337/dc20-1473
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If side effects are a concern, our Zepbound side effects guide covers what to expect at every dose level
Systemic effects reported or plausibly linked to elevated growth hormone and IGF-1 include water retention, tingling or numbness (paresthesia), joint discomfort, headache, flushing, and transient changes in glucose handling
GHK-Cu-Gly His-Lys is a copper-binding tripeptide thats present naturally in human plasma