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24 MhamdiA.HagerJ.ChaouchS.QuevalG.HanY.TaconnatL.et al

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The researchers noted that this peptide elevated melatonin levels in the participants, leading to improved regulation of their sleep patterns [14]

The immunomodulatory metabolite itaconate derived from the TCA cycle was significantly boosted as a result of decreased isocitrate dehydrogenase 2 and increased immune-responsive gene 1 and mitochondrial citrate carrier in dapagliflozin-treated mice, accounting for the inhibitory effect of dapagliflozin on NLRP3 inflammasome activation (155)