Understanding these alternatives requires context: not all patients respond identically to GLP-1 drugs, and genetic factors in peptide signaling can influence individual outcomes
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Sandoval DA, Bagnol D, Woods SC, et al
This finding was significant enough that the tirzepatide drug label now advises patients using oral hormonal contraceptives to switch to or add a non-oral contraceptive method when initiating tirzepatide and after each dose escalation
2 Folate supplementation can correct these haematological effects of B12 deficiency but not the neurological complications, which include neuropathies, such as tingling and numbness in the arms and legs, sensory and motor disturbances, including abnormal gait, and cognitive changes
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