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Natural Killer (NK) cells are a critical component of the innate immune system, responsible for identifying and destroying virally infected cells and early-stage malignancies

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138 However, excessive or chronic inflammation exhausts immune cells due to the constant exposure of T antigens, causing dysfunction with the maintained expression of inhibitory receptors such as PD1 and CTLA4, which alter transcription

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis