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Phase IB/II Study of Lirilumab in Combination with Azacytidine (AZA) in Patients (pts) with Relapsed Acute Myeloid Leukemia (AML)
IF 1 functions as a homodimer which binds to two ATP synthase complexes through interactions with the F 1 and subunits
The safety profile was consistent with GLP-1 receptor agonists, with gastrointestinal events including nausea, vomiting, diarrhea, constipation, or abdominal pain, being most common (affecting 79.6% in the cagrilintidesemaglutide group and 39.9% in the placebo group) but mainly transient and mild to moderate in severity
The reproducibility of subjective appetite scores