In a controlled study of the ClikSTAR reusable insulin pen, 99.6% of patients trained by diabetes specialists successfully delivered three consecutive 40-unit doses, with a 95% lower confidence bound of 98.2% , as reported in this ClikSTAR administration study
The issue may be especially troubling for patients with type 2 diabetes, who are already at higher risk for foot-related complications such as nerve damage and poor circulation
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It does leave a white cast on darker skin tones and can pill under make-up meaning it has a limited use for morning routines
The survey also included a validated questionnaire asking if participants had engaged in specific violent behaviors over the past year
These include severe or persistent abdominal pain that may radiate to the back (possible pancreatitis), signs of gallbladder problems such as upper right abdominal pain, fever, or jaundice, sudden changes in vision (possible worsening diabetic retinopathy), severe vomiting or diarrhea leading to dehydration, and any symptoms of a severe allergic reaction
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