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These mediators contribute to systemic inflammation that has been strongly implicated in asthma pathophysiology [41]

However, more research is needed to confirm its efficacy in

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Solving these challenging problems will promote the design and implementation of treatments and therapies for targeting the many disorders with cerebellar involvement

Xu, B., Yang, M., Li, Z., Zhang, Y., Jiang, Z., Guan, S., et al

Truly disease-modifying treatments would be expected to produce increasingly divergent outcomes between treated and untreated patients over years, and this has not been clearly demonstrated in clinical trials