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Natural retinoid derivatives include retinoic acid (tretinoin), and retinyl esters

GSTP1c varies from the a allele by the substitution of valine for alanine at codon 114

[39] The elderly are at increased risk because they tend to produce less stomach acid as they age, a condition known as achlorhydria, thereby increasing their probability of B 12 deficiency due to reduced absorption

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PMID: 40639867 9 3-Methylcrotonyl-CoA carboxylase deficiency newborn screening in a population of 536,008: is routine screening necessary

A1298C affects the enzyme's regulatory domain, altering SAM-mediated feedback inhibition