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Because berberine already has glucose-lowering effects similar to some diabetes medications, combining it with GLP-1 drugs may amplify those effects

This does not mean these combinations are never used, but they need prescriber oversight

Clinical trials show an average of 34 kg (approximately 45% of body weight) reduction when taking 14mg for 6 months to 1 year

After 24 hours of incubation at 37C, colony counts were performed to quantify surviving bacteria

Exendin-4 therapy still offered an additional benefit on reducing transverse aortic constriction-induced cardiac hypertrophy-caused myocardial damage in DPP-4 deficient rats

A third of Wegovy clinical trial participants lost at least 20% of their body weight