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Folate contents in fresh, non-pasteurized juices were reduced by 1140% in leafy vegetables (beet greens, turnip greens, Romaine lettuce, and carrot greens), by 3249% in root vegetables (beet, turnip, and carrot), and by 49% in broccoli compared to the initial vegetables 403

Challenges include batch-to-batch variability, absence of standardized extraction protocols, and inconsistent concentrations of bioactive constituents, all of which complicate compliance with Good Manufacturing Practice (GMP) standards and hinder reproducibility in clinical trials

10.1016/j.redox.2020.101472 22 ManiS.YangG.WangR