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In fact, it ranked as the second most common symptom reported by Reddit users, despite appearing less prominently in many clinical trials

The pressure from the new volume being injected into the body

Higher doses of vitamin B 12 supplements are recommended for patients taking medications that interfere with its absorption (see Drug interactions)

The injection site should be changed to avoid irritation and ensure even absorption

None of the B12 gets lost in the digestive process

Levels then decreased each day thereafter to baseline 3 to 5 days after the dose.[9] Based on the milk levels reported, the three infants in this study received approximately 0.1 mcg/kg daily of extra vitamin B 12 in breastmilk for 4 to 5 days after the maternal dose