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gonorrhoeae , and that in several meningococcal lineages the island contains an additional gene, kbuT encoding a transporter from the 4-Toluene Sulfonate Uptake Permease (TSUP) family involved in transport of -ketobutyrate, an -keto acid particularly abundant in polymorphonuclear neutrophils (PMNs) (Mhling et al., 2003), which can be metabolized through the MCC, raising the hypothesis of a role of MCC during meningococcal host cell infection (Tal et al., 2025)
Buccal films are thin, flexible oral strips that dissolve against the mucous membrane inside the cheek
3.000 mg/da)
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A Phase I clinical trial established the dosing range of 0.01 to 0.03 mg/kg body weight, with significant tanning after five doses (Dorr et al