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Mutations in SEC63 cause autosomal dominant polycystic liver disease

Semaglutide 2.4 mg (Wegovy) and tirzepatide (Zepbound) are approved for adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

This hormone regulates appetite, slows digestion, and helps control blood sugar levels

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Both are typically administered subcutaneously for systemic effects

This hormone plays a role in appetite regulation, gastric emptying, and glucose metabolism