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(2003) in Wound Repair and Regeneration evaluated GHK-Cus effects on full-thickness wounds in rats

Addressing this concern, Hyderabad-based neurologist Dr Sudhir Kumar took to Twitter to note that while vitamin B12 deficiency is known to cause anaemia, peripheral neuropathy, dementia, psychosis and skin pigmentation, calling for supplementation, excessive vitaminB12 may have adverse effects on health and life. Excess of vitamin B12 may be hazardous 1

GDH also plays an important regulatory role in the stimulation of insulin secretion by amino acids (especially leucine)

Patients with reduced kidney function may require modified dosages or alternative approaches to ensure safe treatment