Oral dihexa is not pharmacologically viable because the peptide is degraded by gastric acid and pancreatic proteases before absorption, resulting in bioavailability below 5%
some experts have advocated lower dosages initially, gradually increasing the dose as puberty progresses, with or without a decrease to maintenance levels
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Research interest centers on the compound's proposed capacity to potentiate HGF activity at the MET receptor, with particular attention to downstream effects on synaptic density and cognitive function-related signalling in neurological research models
This is why insulin, growth hormone, and many other peptide-based medications require injection-oral administration would result in degradation before the compound reaches systemic circulation