FDA approved Mounjaro for Type 2 Diabetes in 2022, and later for weight loss under the brand Zepbound in Nov 2023 (US)

Seek medical evaluation for: Severe abdominal pain , particularly if sharp, persistent, or localized to the upper abdomen or right side, which could indicate pancreatitis or gallbladder disease Signs of dehydration including decreased urination, dark urine, dizziness, rapid heartbeat, or extreme thirst Symptoms of hypoglycemia such as sweating, shakiness, confusion, irritability, dizziness, or blurred vision (risk is low with these medications alone but increases when combined with insulin or sulfonylureas) [16] [17] Persistent nausea lasting more than a week despite dietary modifications Inability to tolerate any food or liquids Symptoms of gastroparesis such as severe bloating, early satiety with very small amounts of food, or vomiting undigested food hours after eating Signs of gallbladder problems including right upper quadrant pain, fever, or yellowing of the skin or eyes (jaundice) Rare but serious complications require emergency care

Eat lots of nutrient-dense, high-protein foods such as fish, eggs, Greek yogurt, cottage cheese, nuts and seeds
Theyre in a class of drugs called GLP-1 agonists, which mimic a hormone that helps reduce food intake and appetite
Why PFAS Are Called Forever Chemicals PFAS are often referred to as forever chemicals because they do not break down easily in the environment or the human body
The random effect model was used to quantitatively synthesize the main MR results (IVW method) of the discovery cohort and the validation cohort