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This approach ensures sustainable weight loss, as rapid weight reduction over a short period may increase the risk of the yo-yo effect or regaining weight after discontinuing the medication

In a clinical trial of more than 3,000 adults with obesity, participants who received the highest dose of orforglipron, 36 milligrams, lost 11.2% of their body weight -- about 25 pounds on average -- over more than 16 months

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Current status of glucagon-like Peptide-1 receptor agonists in metabolic dysfunction-associated steatotic liver disease: a clinical perspective

By identifying and titrating at the patients pace , we can improve tolerability

Bisacodyl (Dulcolax)