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4.3 GSH metabolism: a central hub in mid-late SAE The hippocampus, with its high metabolic demands and low antioxidant capacity, is uniquely vulnerable to septic injury (Yuan et al., 2020)

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Based on these limitations, we propose that future research should focus on the following specific directions: clarifying the upstream regulation mechanism, developing more complex experimental models, and promoting the transformation of clinical to precision medicine

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