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what the non-pharmacological management should be, when to initiate pharmacological treatment, how to achieve the treatment goal effectively

Despite decades of intensive research, the exact mechanisms driving the onset and progression of AD remain incompletely understood, underscoring the urgent need for continued investigation into its pathophysiology and the development of effective therapeutic interventions (Korczyn and Grinberg, 2024)

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What the research does not show is a strong dose-response curve beyond 10 mg

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