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NAPQI is neurotoxic : Crosses the placenta, depletes fetal brain glutathione, generates oxidative stress, and triggers cell death in neural tissue at doses below those causing maternal liver toxicity

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The Phase IIb efficacy trials did not meet their efficacy endpoints, and clinical development for the original therapeutic indication was halted

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Les premiers ressentis (nergie pendant l'effort) peuvent arriver en quelques jours, mais l'effet sur la composition corporelle ncessite plusieurs semaines