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It stimulates the TGF-beta pathway, which organizes collagen structure and promotes tissue contraction

Simple timing framework Baseline Discuss baseline labs before starting, especially with diabetes risk, cancer history, edema, nerve symptoms, or active growth-related medical concerns

Sung WS, Kang HR, Jung CY, Park SS, Lee SH, Kim EJ

No significant concerns in trials

Electronic clinical outcome assessment (eCOA) platforms, such as Medable and Clinical Ink, enable patients to report symptoms and QoL metrics in a timely and structured manner

Irradiation of imipramine and amitriptyline induces production of singlet oxygen