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Tip: Use grapefruit as a meal starter: eating half before lunch or dinner fills stomach space, and research suggests it can meaningfully reduce how much you eat at the meal that follows

R-ALA is the naturally occurring bioavailable form of the compound

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Those with weight loss resistance, insulin resistance, prediabetes, or metabolic slowdown

One notable study is the SUSTAIN 6 trial, which involved over 3,000 participants with type 2 diabetes and established cardiovascular disease