The number on the scale starts to drop
Cortisol increases blood sugar, promotes fat storage particularly around the abdomen, increases appetite for high-calorie foods, disrupts sleep, and impairs gut function all factors that GLP-1 medication is working to improve
Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice
Long-term benefits include cardiovascular risk reduction and potential renoprotective effects in appropriate patients
Weight regain following bariatric surgery represents a significant clinical challenge, with studies suggesting it affects a substantial proportion of patients within 25 years post-operatively
That means employers are absorbing significant pharmacy costs without consistently seeing the health outcomes that would justify the investment through reduced downstream medical spending