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[85] conducted the first descriptive analysis of the characteristics of Adverse Event Reports (AER) documenting the misuse and abuse potential of semaglutide compared to other GLP-1RAs (e.g., albiglutide, dulaglutide, exenatide, liraglutide, lixisenatide, and tirzepatide) by analyzing the FDA Adverse Events Reporting System (FAERS) pharmacovigilance data set

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10.1016/j.mam.2008.05.005 [DOI] [PMC free article] [PubMed] [Google Scholar] Lu S.C

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The economics differ significantly because tirzepatide is available as a commercial pharmaceutical product while retatrutide is currently a research compound