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Long-Term Effects and Safety : There's also mention of a need for caution with long-term use, referencing studies that have shown potential negative effects on the thyroid and hormonal systems in some cases 4

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Petrasek J, Bala S, Csak T, Lippai D, Kodys K, Menashy V, et al

Pre-cycle testing Before starting IGF-1 LR3, establish baseline values for: Fasting glucose and insulin HbA1c (long-term blood sugar marker) IGF-1 levels Complete metabolic panel Lipid panel These baselines allow comparison during and after cycles to identify any negative trends

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Patients seeking tirzepatide specifically for type 2 diabetes management should discuss Mounjaro with their healthcare provider, as it carries the appropriate FDA indication for diabetes