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doi: 10.1038/s43018-023-00647-3

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Cytoplasmic mitochondrial precursor proteins are protected and unfolded by chaperone proteins such as Hsp90 in the cytoplasm before entering mitochondria

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In this review, not only do the authors point to the usefulness of serum periostin as a TH2 biomarker but they also suggest that, at least in skin, periostin is crucial for amplification and persistence of allergic inflammation by communicating between fibroblasts and keratinocytes

Timing: Some medications are administered daily, while others may require weekly injections