Although intensified glycemic control, blood pressure management, and inhibition of the reninangiotensin system (RAS) can slow DKD progression, its clinical course remains highly heterogeneous
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It is expected to lead to increased interest in SCFAs studies as an important regulator in CNS diseases and provide feasible suggestions based on SCFAs for the therapy of CNS diseases in the future
Mller TD, Finan B, Clemmensen C, et al
Overall, GLP1 agonists show central effects on brain regions involved in energy balance and cognition and may act in parallel to, rather than simply downstream of, insulin to modulate neuronal activity and glucose utilization
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