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While the etiology of NTD is multifactorial, some studies have found that blood concentrations of homocysteine or holo-transcobalamin to be lower in NTD-affected infants and mothers compared to non-affected controls (reviewed in 59)

Clean fluid is delivered to the Gray Water Holding Tank

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Furthermore, different methods of administrationoral, intraperitoneal and topicalcan be compared in order to establish a systemic effect