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Both can cause digestive upset (nausea, bloating, diarrhea), appetite suppression, and changes in blood glucose

An enlargement of the red blood cells can also occur as part of a folic acid deficiency, which is why the folic acid value is usually determined in the blood at the same time in these cases

Bravo B et al

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25.7 g/mL in controls)

tolerability comparable to placebo with fewer dropouts