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Peptide Synthesis and Purification Solid-phase peptide synthesis method Synthesis process: The synthesis of BPC 157 usually adopts the solid-phase peptide synthesis method, and the polypeptide chain is constructed by gradually adding amino acid residues

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Cell Metab (2016) 24(1):4150.10.1016/j.cmet.2016.05.005 184 KowlgiNGChhabraL

Severely obese patients (BMI 35+) show markedly reduced response regardless of dose

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That would sound like a moderate strain