This warning is based on rodent studies showing increased risk, although no clear link has been found in humans
For most people, side effects are most noticeable during the first few days after the initial injection or following a dose increase
As mentioned, DPP-4 inhibitors increase the concentration of endogenous GLP-1, leading to increased insulin secretion, decreased glucagon secretion, and decreased HbA1c in patients with T2DM
At the same time, growing environmental challenges, such as rising air pollution and exposure to dry air, underscore the urgent need to strengthen airway defences
Notably, oral semaglutide introduces a unique pharmacomicrobiomics paradigm compared to subcutaneous formulations
Infertility is more common in obese men than those with normal weight