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In contrast, the GLP-1RAs exendin-4 and liraglutide reduced these cholesterol levels (Fig

Figure 5 illustrates the antidiabetic mechanism of polyphenols in the human body, showing deconjugation in the gastrointestinal tract, absorption, hepatic portal circulation, reconjugation in the liver, biliary excretion, renal excretion, and microbial deconjugation in the colon, ultimately leading to fecal excretion

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