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Patients are flocking to compounded weight-loss drugs, but are they safe

Related Stories Newer GLP-1 medications may reduce alcohol-related hospitalization risk Generic semaglutide could improve diabetes treatment affordability in Canada Alcohol use during pregnancy increased in the United States from 2011 through 2024 Simultaneously, a growing body of evidence suggests that Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs) are capable of crossing the blood-brain barrier (BBB) and interacting with the brain's reward and dopamine signaling regions, leading researchers to hypothesize that these originally weight-management-centric drugs could be used to address addictive behaviors, specifically regarding the suppression of ethanol-seeking triggers

Spicy foods may exacerbate nausea in some patients, especially those already experiencing gastrointestinal sensitivity from semaglutide

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It activates GLP-1, GIP, and glucagon receptors at the same time

The other three are unannounced GPCR targets