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Discovery of a novel GLP-1/GIP dual receptor agonist CY-5 as long-acting hypoglycemic, anti-obesity agent

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The glucagon receptor activation appears to contribute to quicker metabolic response, while the GIP component may help reduce early nausea that can slow initial adaptation to GLP-1 medications

Red Flags Nausea on GLP-1 Therapy: When It Is a Dose Issue and When It Needs Attention Nausea is one of the most common side effects patients ask about during GLP-1 therapy

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