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If you observe any cloudiness, color changes, or visible particles floating in the solution, you should discard it immediately as it may be contaminated or degraded

Ratzke, C., Denk, J

E., Comelli, F., Giagnoni, G

Siebenhofer A, Winterholer S, Jeitler K, Horvath K, Berghold A, Krenn C, et al

During the standard titration protocol, patients typically begin at 0.25 mg weekly and increase gradually over 16 weeks, reaching a maintenance dose of 2.4 mg

Overall, out of 304 participants, 282 (92.8%) concluded the trial by attending the end-of-trial safety evaluation, 272 (89.5%) underwent body weight assessment at the week 104 end-of-treatment visit to determine the long term effects of semaglutide, and 243 (79.9%) adhered to the treatment protocol until the end-of-treatment visit (Fig