Studies that included NOACs and warfarin have shown that timing a procedure further out from NOAC dosing, the use of atraumatic techniques, and employing local hemostatic measures resulted in minimal adverse outcomes
Review of causes of medication discontiuation
Hampel H, Mesulam MM, Cuello AC, Farlow MR, Giacobini E, Grossberg GT, Khachaturian AS, Vergallo A, Cavedo E, Snyder PJ, Khachaturian ZS (2018) The cholinergic system in the pathophysiology and treatment of Alzheimers disease
Proc (Bayl Univ Med Cent) 23: 1920, 2010 [DOI] [PMC free article] [PubMed] [Google Scholar] 26.Wong YL, Koh J: Case report: Pyroglutamic acidaemia as a likely cause of high anion gap metabolic acidosis
Do not use if tamper-evident seal is broken or missing
Can also be taken orally for direct gut benefit