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These data showed that subchronic (7 to 14 days) exendin-4 or liraglutide administration in rodents resulted in hyperactivation of the HPA, disruption of glucocorticoid circadian secretion, hypertrophy of the adrenal gland, and dysregulation of pituitary-adrenal stress responses [77]

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doi: 10.1016/j.biomaterials.2022.121586 124 RaghuGvan den BlinkBHamblinMJBrownAWGoldenJAHoLAet al

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