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Unlike minoxidil, which can cause unwanted facial hair through systemic absorption, topical copper peptides applied to the scalp typically don't cause facial hair growth

For example, icariin (ICA) can upregulate GPX4 expression, reducing MDA levels and iron content in synovial cells, thereby activating the System Xc /GPX4 axis to inhibit ferroptosis and alleviate synovial inflammation (Wang et al., 2016

Fitch CD, Chevli R

As such, the ascorbate both suppresses free radicals and stimulates the oxidant system on the cells while acting on antioxidant enzymes as a ROS eliminator [51]

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Thymosin 4 is characterized biochemically as an actin-sequestering peptide (it binds monomeric G-actin)