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The decision between long-term and short-term use should be individualized, considering factors such as degree of obesity, presence of complications, treatment response, side effect profile, cost and insurance coverage, and patient preferences and goals

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Semaglutide is used to treat Type 2 diabetes mellitus as monotherapy (if metformin inappropriate), or in combination with other antidiabetic drugs (including insulin) if existing treatment fails to achieve adequate glycaemic control