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In this test, mice sensitized by a comparatively rigorous regime (the intradermal injection of adjuvant followed by the daily application of the test material, for 4 consecutive days, to tape-stripped skin) are challenged on one ear with the test compound and on the contralateral ear with vehicle alone

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The study concluded that feeding mice with a selenium-deficient diet for 6 months led to the depletion of renal GPx activity by 17% but did not alter renal radiosensitivity as compared to the mice fed with a selenium-adequate diet