doi: 10.1038/s41467-022-28683-0 111 FriasJPNauckMAVanJKutnerMECuiXBensonCet al
But they underscore the importance of careful medical oversight
GLP-1 receptor agonists (GLP-1RAs) are widely used in the treatment of type 2 diabetes (T2DM) due to their attributes such as body weight loss, protection of islet cells, promotion of islet cell proliferation and minimal side effects
Targeted oral peptide delivery using multi-unit particulates: Drug and permeation enhancer layering approach
Thus, drugs that target GIP, GLP-1, or GLP-2 receptor signalling pathways could be employed for treating bone diseases
Of medical importance, the discovery of the DPP-4 protease resistant exendin-4 from venom of Heloderma suspectum paved the way for the successful development of GLP-1 analogues as important treatments for insulin resistant type 2 diabetics