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Loraine Baraki MHT, weight & testosterone 27:29 The cardiometabolic shift: cholesterol at the FMP 30:18 Insulin resistance & metabolic syndrome 33:12 Blood pressure & 10-year heart risk 34:54 Clinic: the "estrogen crisis" lipid panic 39:13 Bone: the advice vs the data 40:34 Why DXA misses most fractures 41:24 LIFTMOR: lifting heavy with low bone density 44:47 The LIFTMOR results 46:53 Lifting vs Pilates, and falls 52:17 Clinic: "Should I be deadlifting?" 56:14 Cognition & brain fog 57:50 Why brain fog is mostly a sleep problem 59:17 Clinic: brain fog, night sweats, broken sleep 1:03:06 Depression & dementia in midlife 1:05:43 Does hormone therapy protect the brain

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PMID: 28911075

p53s potential as a tumor suppressor is well-documented, primarily functioning to stop the proliferation of cells that have suffered DNA damage

MC: Writing original draft, Writing review & editing

This is followed by the activation of the STAT3 pathway and the induction of M2 polarization, accompanied by upregulation of IL-10 (117)