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The TMLHE gene (N-trimethyllysine dioxygenase enzyme) is used in the first step of synthesis, along with iron and vitamin C

10.1007/s00125-014-3292-y [DOI] [PubMed] [Google Scholar] 75.Whim MD

If youre on a GLP-1 medication such as semaglutide (Ozempic) or tirzepatide (Mounjaro) for type 2 diabetes, or semaglutide (Wegovy), tirzepatide (Zepbound), or orforglipron (Foundayo) for weight loss, you probably know that your food and beverage choices make a big difference in how well you do on these drugs

Therefore, the modification reactions of MTs by various compounds are influenced by the partial transfer of Zn(II) to PAR due to a competitive process