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Multi-center comparisons and universal standardization of the used techniques would to a large extent improve miRNAs reliability

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The total weight loss by 3 months averages 510% of starting body weight in clinical studies, with continued loss possible over 612 months with dose optimization

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ROS react with PUFAs in the lipid membrane [17, 18] to induce lipid peroxidation, thereby triggering intracellular ferroptosis [19, 20]

P = 002) were significantly higher in the test group compared with the control group within plasma (online Supplementary Table 3a)