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The participants diets were not standardized and they were asked not to change their dietary habits during the course of the study

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1169/2011) Content: 0.019 kg (734.21 / 1 kg) Tip L-Methionine 1500mg | fair-pure L-Methionine 1500 mg capsules contain the sulfur-containing, essential amino acid L-methionine, which the body cannot produce itself and therefore must be obtained from the diet

10.1038/s41467-017-01291-z 94 LalondeM.ChartrandP

however, this can vary from patient to patient