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In HF mice without diabetes, dapagliflozin, an inhibitor of sodium-glucose-linked transporter 2, decreased EndMT brought on by ISO via deacetylating and breaking down NICD by SIRT1 (Wang W

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Specifically, SOD1 catalyzes the conversion of O 2 - into H 2 O 2 , thereby reducing the levels of ROS and mitigating oxidative stress [37]

Recombinant human GPX4 alleviated ISO-induced myocardial ischemia injury [250]

S1 were also in good agreement with the more balanced ratios of the rate constants for the corresponding (de)glutathionylations from Table 1